Spike Lee

Director

Teyonah Parris

Lysistrata

Nick Cannon

Demetrius 'Chi-Raq' Dupree

Wesley Snipes

Sean 'Cyclops' Andrews

Angela Bassett

Miss Helen Worthy

Samuel L. Jackson

Dolmedes

John Cusack

Fr. Mike Corridan

Jennifer Hudson

Irene

David Patrick Kelly

General King Kong

D. B. Sweeney

Mayor McCloud

Dave Chappelle

Morris